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NeuroSim

Simulator

A spiking circuit integrating on your own hardware. The controls change the equations, not a playback speed.

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The model

Published parameters, not chosen ones.

Each neuron holds a membrane potential and a synaptic drive term. Both decay between events. A presynaptic spike adds a step proportional to the number of synapses in that connection, signed by the presynaptic transmitter. At threshold the cell fires, resets, and is refractory for a fixed interval.

The defaults are the published constants of the whole-brain Drosophila model of Shiu, Sterne and colleagues. Every one of them is adjustable above, but results then describe your parameterisation rather than the reference model.

Resting potential
-52 mV
Firing threshold
-45 mV
Membrane time constant
20 ms
Synaptic time constant
5 ms
Refractory period
2.2 ms
Propagation delay
1.8 ms
Weight per synapse
0.275 mV

Shiu et al. 2024, Nature 634:210

Library

Four circuits.

  1. 01

    Mushroom body

    Mushroom body / antennal lobe

    Sparse expansion coding with global inhibitory normalisation.

    2,089 cells

  2. 02

    Central complex

    Ellipsoid body / protocerebral bridge

    Ring attractor maintaining and rotating a heading estimate.

    176 cells

  3. 03

    Optic lobe (T4/T5)

    Lamina / medulla / lobula plate

    Retinotopic elementary motion detection, ON and OFF pathways.

    2,604 cells

  4. 04

    Null model

    None (synthetic)

    Unstructured random network, the experimental control.

    1,200 cells

Limits

What this is not.